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Turning DNA data into action with whole genome insights

Unlock the new era of precision health with Inocras

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What We Do

Inocras is on a mission to transform how the world diagnoses and treats genetically driven diseases.

With a specialization in cancer and rare diseases, our whole genome bioinformatics platform derives actionable insights by analyzing your unique genomic makeup.

Genetic testing has evolved significantly: From targeted panels (300-500 genes), to exome sequencing (focusing on only protein-coding areas). Now, with whole genome sequencing, our platform covers the whole genome including protein-coding (exons), non-coding (introns) and mitochondrial DNA.

At the forefront of whole-genome technology, our advanced diagnostics platform offers personalized insights tailored to you, putting precision health within everyone’s reach.

Why Whole Genome?

Standard panel testing looks at less than 0.1% of your genome1, and whole exome sequencing 1-2%2, leaving plenty of room for unanswered questions. Recent studies revealed that complicated mutations are often not captured in standard panel testing and whole exome sequencing. Our whole genome sequencing platform gives enhanced clarity, by offering a broader and more detailed analysis of your genetic makeup. Did you know…

> 25%

of cancer patients have complicated mutations

(structural variations and/or variants in non-coding regions) that are often missed in standard panel sequencing and exome sequencing2.

10-20%

of additional diagnoses in rare diseases

by whole genome sequencing thanks to its extensiveness, compared to standard panel and exome sequencing.3, 4,5

What We Provide

We see more than 99% of your genetic makeup.

Standard panel sequencing analyzes less than 0.1%6 of your genome, whole exome sequencing 1-2%7, leaving plenty of room for unanswered questions. Our whole genome sequencing platform offers a broader and more detailed analysis of your genetic makeup. This gives enhanced clarity when it comes to your health.

We help you understand the data so you can make informed decisions.

Having more data doesn’t automatically mean it’s easier to understand. Our proprietary bioinformatics platform is designed to thoroughly analyze all of your genomic data and translate it into meaningful findings. Our user-friendly reports empower you to confidently navigate your genetic information, assisting you in making informed decisions throughout your journey.

We support you with services that help you take action.

Our mission does not end simply by providing insights. We are here for you — patients, physicians, and researchers — helping you to fully understand your test results with our in-house clinicians and experts. We also connect patients to matching clinical trials.

Our Products

Whether you’re seeking additional insights for cancer treatment options or navigating a diagnostic journey for a rare disease, our genomic tests provide valuable information to aid your next steps.

CancerVision

Supports you to explore a wider range of treatment options.

  • Cancer profiling solution for solid tumors
  • Extensive analysis of the whole genomic makeup of your cancer
  • Easy-to-read report with actionable treatment options
  • Enhancing opportunities for clinical trial participation for new therapeutics
  • Genetic counseling support for patients and physicians

RareVision

Shorten the rare disease diagnostic odyssey.

  • Identify genes associated with rare diseases from one of the most up-to-date databases8
  • Extensive analysis of the whole genomic makeup of your disease
  • Genetic counseling support for patients and physicians

Case Studies

New Hope for a Breast Cancer Patient

Sarah, a 52-year-old woman, was diagnosed with stage IV breast cancer and wasn’t responding to immunotherapy or chemo treatments. Her provider ordered the CancerVision test from Inocras, which pinpointed a large structural change (germline large deletion in the RAD51C gene) that wasn’t found in other types of genetic tests. This finding led to the decision to enroll her in a clinical trial, which brought her clinical improvement.

Case Studies

Family Finds Answers for Perplexing Symptoms

Andrew, a 1-year-old boy, was experiencing a myriad of perplexing symptoms, including decreased muscle tone, dysmorphism, and a failure to thrive. With the hope of finding answers, Andrew’s provider ordered the RareVision test. The results revealed a pathogenic variant that led to a definitive diagnosis of a rare genetic disorder called Noonan syndrome. This finding provided a roadmap for his future care that allowed his family to take proactive steps in managing his health.

**While all patient names provided are fictionalized to ensure privacy and confidentiality, the age, disease information, and diagnostic process in the testimonials are based on real cases. Please note that clinical outcomes may vary for each individual.

5 Myths About Whole Genome Sequencing

Wouldn’t whole genome sequencing (WGS) usually have lower depth reading vs. targeted panel sequencing due to its broader coverage?

Our test utilizes Target-Enhanced WGS, which combines the advantages of targeted panels and WGS. For our CancerVision test, for example, we achieve an average of 500x the depth for over 500 critically important genes, which is comparable to the best-in-class panel sequencing depth, and 40x the depth for the entire genome, providing comprehensive coverage beyond the targeted genes9.

Does whole genome sequencing give me too much data, making it hard to understand?

Inocras provides an easy-to-understand report using our proprietary algorithm. This algorithm ensures that the report focuses on the most relevant and actionable findings.

Our report highlights actionable findings that have implications for treatment options and other relevant findings related to genomic instability and germline analysis. By focusing on these key areas, our report delivers the clinically critical and relevant information to healthcare providers and patients.

Standard panel sequencing is developed around available treatments. Wouldn’t the WGS insights be less helpful if there is no available treatment?

Our findings cover more than just known genetic variations with treatment options. We also uncover copy number variations, structural alterations, and other genome-wide signatures that help inform clinical decisions. This approach aims to provide comprehensive genetic insights, reducing the need for further tests. Plus, our reports list any relevant clinical trials available today.

Even if treatments or clinical trials aren’t available right now, patients will receive information about mutations that might create opportunities for participation in future clinical trials.

Isn’t the testing expensive vs. a panel test?

We provide valuable genomic information at a comparable price to the average standard panel sequencing test.

Doesn’t it take longer time vs. panel sequencing?

We prioritize delivering results promptly and aim for efficiency in our processes. Our current turnaround time is 14 days from receipt of samples on average, aligning with the industry’s best-in-class testing standards.

This ensures patients receive their results in a timely manner, enabling healthcare providers to make informed decisions about their care. However, please note that the time from ordering the test to receiving results may vary depending on how long it takes for samples to reach our laboratory.

Frequently Asked Questions

How can I order a test as a patient?

To order a test, you’ll need to have a conversation with your doctor, who can then order the test for you. Our tests are currently not available for ordering without the guidance of a licensed healthcare provider.

How can I order a test as a provider or a researcher?

To order a test, please download and complete the test requisition form and email it to inquiry@inocras.com.

What kind of samples are collected?

CancerVision will require tissue and blood samples while RareVision will require a blood sample. Providers and researchers will receive detailed sample collection requirements in an instruction sheet once the test is ordered.

How are the test results shared?

Test results are shared with the provider who ordered the test. The provider will then share the results with the patient.