Whole genome de novo sequencing:

Our de novo sequencing accurately characterizes any species without a reference sequence available for alignment.

Whole genome re-sequencing:

Our WGS process provides a comprehensive analysis of the genome, including SNVs, insertions & deletions, CNVs, and SVs,using a reference genome. This information can be used to discover candidate genes associated with disease and drugresponse, enabling personalized precision medicine.

Sequencing platform and product

Human Leukocyte Antigen (HLA):

Accurate and cost-effective HLA typing with our NGS-based approach, performed by experienced scientists and technicians committed to quality outcomes. Trust us to meet your program requirements with fast, reliable results.

Chromatin-immunoprecipitation (ChiP):

Unlock insights into protein-DNA interactions and histone modifications across the genome with our ChiP-Seq services. Benefit from our expertise in ChiP assays, sonication optimization, and bioinformatics, and obtain high-quality data for your research.

TCR/BCR Bulk Sequencing:

Our repertoire sequencing services use NGS technology to accurately detect and analyze T and B cell repertoires for both bulk and single cell analysis. Gain insights into the immune system's fundamental processes in healthy individuals and uncover mechanisms behind autoimmune diseases, allergies, cancer, and aging.

Transcriptome Sequencing

mRNA/ Total RNA sequencing:

Our RNA sequencing service, utilizing NGS technology, provides precise and sensitive measurement of gene expression levels across transcriptomes. With our service, you can detect changes caused by disease, treatment response, and environmental factors, gaining insight into gene-enabled research and expression control. We also offer detection of novel transcriptomes, fusion genes, alternative splicing, and mutations, providing a comprehensive view of gene regulation and expression control for research in biomarker development, disease diagnosis, and monitoring.

Single Cell Multi-omics Sequencing

Single cell RNA sequencing:

Our scRNA-seq services use NGS technology to analyze gene expression in individual cells, enabling the study of complex cell processes and the identification of cellular heterogeneity and rare cell populations. Unlike bulk RNA sequencing, which provides average values by combining various cells, ScRNA-seq separates a group of cells into single cells for analysis. This approach is particularly valuable for investigating live tissues, which are composed of diverse cell types with unique functions and heterogeneity between subpopulations of cells.

Single nucleus RNA sequencing:

Our single cell nucleus RNA sequencing technology overcomes limitations in analyzing sensitive cells that are easily damaged or difficult to separate. By analyzing the transcriptome of a single nucleus, this method eliminates stress and bias that may occur during single cell separation. Unlike scRNA-seq, which works best with fresh tissue samples, single cell nucleus RNA sequencing allows for analysis of frozen samples and transcription from tissues that are difficult to separate.

Single cell immune profiling (TCRs, BCRs):

Our single cell immune profiling services utilize VDJ and VJ gene sequencing to analyze the diversity of clonotypes at the single cell level, allowing for precise immune profiling of T cell receptors and B cell receptors.

Single cell ATAC sequencing:

Our single cell ATAC sequencing technique uses transposase to assess genome-wide chromatin accessibility by inserting sequencing adapters into open chromatin regions. This approach analyzes the DNA release information in a single nucleus while mapping binding sites of transcription factors and nucleosome locations. By identifying cell-specific binding sites and activity of transcription factors, researchers can gain insights into cell-specific functions when analyzing a single cell.

Sequencing platform and product